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TG Therapeutics lifts 2026 revenue outlook to about $1 billion after Q3

TG Therapeutics reported Q3 2026 revenue of $259.9 million, including $232.6 million in US BRIUMVI sales, and raised full-year guidance from about $950 million.

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TG Therapeutics raised its full-year 2026 revenue guidance on November 9 after reporting third-quarter results, according to the company's release. The multiple sclerosis drugmaker now expects total global revenue of about $1 billion for 2026, up from about $950 million previously.

Third-quarter results

  • Total global revenue: $259.9 million.
  • BRIUMVI US net product revenue: $232.6 million, about 52% higher than a year earlier.
  • Share buybacks: about $100 million of shares repurchased during the quarter, the company said.

StreetInsider reported that quarterly earnings per share of $0.35 came in $0.02 below the analyst estimate of $0.37, while revenue beat the consensus estimate of $245.47 million.

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Updated 2026 guidance

TG Therapeutics' new targets for 2026:

  • Total global revenue of about $1 billion, up from about $950 million.
  • BRIUMVI US net product revenue of about $915 million to $920 million, up from $890 million to $905 million.
  • Operating expenses (R&D and SG&A, excluding non-cash compensation) of about $450 million to $500 million, unchanged. This includes subcutaneous BRIUMVI manufacturing costs and start-up costs for a second manufacturer.

What management expects next

"With solid third-quarter performance and a strong fourth quarter anticipated, we are on track to exceed $1 billion in global revenue in 2026, less than four years after launching BRIUMVI," said chairman and CEO Michael S. Weiss.

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Weiss listed several catalysts for the next 18 to 24 months:

  • Pivotal Phase 3 results for subcutaneous BRIUMVI, expected around year-end 2026 or early 2027.
  • A possible launch of a simplified IV starting regimen in mid-2027, following the Phase 3 ENHANCE trial.
  • A possible launch of subcutaneous BRIUMVI in 2028.

The company also pointed to data presented at MSToronto2026, including seven-year follow-up from its ULTIMATE I and II Phase 3 trials.

This article is for information only and is not investment advice. Company guidance is a forecast and may change.

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  1. TG Therapeutics Reports Third Quarter 2026 Financial Results and Raises Full-Year Revenue Guidance (external source) TG Therapeutics
  2. TG Therapeutics (TGTX) Misses Q3 EPS by 2c; Offers Guidance (external source) StreetInsider